As Mark said above, your going to lack bass in any form of 6x4/6x9 or anything.
Best result you’d want separate component speakers but you wouldn’t be able to do this without modification to the doors.
I’d recommend what the guys above are saying with 6x4 doors and a sub in the boot. I’m running a full inphase set up which are a fairly cheap brand but not highly known quite impressed with them if I’m honest.
I’m also running a 10 band eq which I can’t recommend enough but it depends how much your into your music I guess.
Here a slightly old picture of my boot as I don’t use the car daily it suits me well.
Seat Leon 1.8T 20V - Track Car
VW Scirocco Scala 1.8 Inj - Toy
Ford Transit 2.0 - Work Horse